Using a simple and efficient pre-treatment methods QuEChERS （Quick, easy, cheap, effective, rugged, and safe）, the residues of 13 pesticides （chlorothalonil, triadimefon, fipronil, procymidone, endosulfan, bifenthrin, fenpropathrin, cyhalothrin, pyridaben, cyfluthrin, cypermethrin, fenval- crate and deltamethrin） in pitaya （Hylocereus undulatus Britt） were analyzed with gas chromatography-e- lection capture detector （GC-ECD） that were compared with regular extraction and solid phase extraction （SPE） purified method. The results showed that the limits of detection were in the range of 0. 009 - 0. 400 ng/g. The average adding recoveries ranged from 81.1% to 108.0% with relative standard deviation of 6.6% - 17.0%. Adding recoveries of different extraction and purification methods were close, and relative standard deviation of SPE were relatively large. The method with less organic solvents, reliable, high aceuraey and precision would be applied in the local laboratory with gas chromatography to carry out rapid detection of pesticide residues in pitaya.