Abstract：As an important component of innate immunity, inflammatory bodies play an important role in the body's immune response and disease development. ASC is a key protein in the inflammatory body that connects cytoplasmic receptors and Caspase-1. In order to further understand the inflammatory system of goose, the primers were designed with reference to the predicted sequence report in NCBI (XM_013201308.1) , and the ASC gene of Magang goose was cloned, and bioinformatics analysis and tissue expression difference were carried out. The results showed that the complete ORF region of the go-ASC gene was 663 bp in length and encoded 220 amino acids. Homology analysis showed that the go-ASC gene sequence has low homology with that in mammals (41.0%～52.6%) , and the domain is also largely different. It only contains CARD domain and lacks PYD domain. The results of tissue expression showed that the go-ASC gene was mainly expressed in blood and mucosal epithelial tissues, and the expression level was the lowest in muscle tissue.
2019, Vol. 32 
