Abstract：Due to the increasing antibiotic resistance, it's urgent to develop new antibacterial drugs. Water-soluble silica has attracted much attention because of high stability, no drug resistance, and good antibacterial effects. However, the application of it has not been reported in aquatic field in detail. In this paper, five aquatic bacteria (Bacillus subtilis, Escherichia coli, Vibrio parahaemolyticus, Aeromonas hydrophila and Staphylococcus aureus) were selected to study the antibacterial effects of water-soluble silicon. The results showed that water-soluble silica had significant growth inhibitory effects on five bacteria when the concentration is higher than 500 mg/L, and the inhibitory effects were different according to the different bacteria. Furthermore, the scanning electron microscope (SEM) was used to analysis the morphological changes of Aeromonas hydrophila and Staphylococcus aureus after the water-soluble silica treatment. The results showed that the water-soluble silica treatment could cause shrinkage, adhesion, and structural destruction of bacteria. The present study provides a new reference for “non-anti” drugs.
2021, Vol. 34 
