Abstract:Environmental factors play an important role in animal reproduction, mainly by regulating secretion of reproductive hormones in the hypothalamus-pituitary-gonadal axis. Gonadotropin-inhibitory hormone(GnIH), as an important reproductive inhibitor of hypothalamic secretion, plays an important role in mediating animal reproduction. The mechanism of GnIH in light, stress, population effects on animal reproduction and steroid hormone negative feedback regulation in animal was comprehensively and systematically reviewed to provide reference for subsequent GnIH related research.